How Omic Works

A technical deep-dive into our AI-driven drug discovery platform: from multi-omics data to clinical candidates

The Core Innovation

Omic combines autonomous AI scientists with mechanistic digital patient models to discover drugs at unprecedented speed and accuracy. Our platform doesn't just predict—it reasons, hypothesizes, experiments, and learns.

Platform Architecture

1. Data Integration Layer
Genomics • Transcriptomics • Proteomics • Metabolomics • Clinical Data • Literature
2. Digital Patient Engine
Mechanistic Models • Pathway Networks • Disease Signatures • Patient Archetypes
3. Autonomous AI Scientists
Hypothesis Generation • Experiment Design • Analysis Pipelines • Result Interpretation
4. Discovery Outputs
Validated Targets • Novel Molecules • Efficacy Predictions • Safety Profiles • Biomarkers

The Discovery Process

1

Multi-Omics Data Integration

We ingest and harmonize data across all biological layers: DNA sequences and variants (genomics), gene expression patterns (transcriptomics), protein abundance and modifications (proteomics), and metabolite profiles (metabolomics).

Data Sources:
RNA-seqWGS/WESMass SpecscRNA-seqATAC-seqClinical EHR
2

Digital Patient Construction

We build mechanistic models that simulate patient biology at the molecular level. Unlike black-box predictions, our digital patients capture the actual causal relationships between genes, proteins, pathways, and disease phenotypes.

Pathway Networks
Curated signaling cascades with quantitative parameters
Disease Signatures
Molecular patterns distinguishing disease from health
Patient Archetypes
Population clusters with distinct molecular profiles
Drug Response Models
Predictions of therapeutic effect per patient type
3

Autonomous AI Target Discovery

Our AI scientists operate autonomously—forming hypotheses, designing computational experiments, analyzing results, and iterating. They work 24/7, exploring hypothesis spaces no human team could cover.

AI Capabilities:
  • Read and synthesize scientific literature in real-time
  • Generate and test mechanistic hypotheses about disease
  • Write custom analysis code and ML models
  • Identify and validate druggable targets
4

Generative Molecule Design

Once targets are validated, we generate novel small molecules optimized for potency, selectivity, and drug-like properties. Our generative models explore chemical space efficiently, producing candidates with favorable ADMET profiles.

10K+
Molecules generated per target
<1nM
Predicted binding affinity
95%
Pass drug-likeness filters
5

Virtual Clinical Simulation

Before any molecule is synthesized, we simulate its effects across our digital patient populations. This predicts efficacy, identifies responder subgroups, optimizes dosing, and flags potential safety concerns.

Simulation Outputs:
• Predicted response rates by patient subgroup
• Optimal dosing regimens
• Biomarkers for patient selection
• Off-target effect predictions
• Combination therapy synergies
• Resistance mechanism forecasts
6

Clinical Candidate Nomination

Candidates that pass all computational validation proceed to wet lab confirmation and clinical development, with comprehensive dossiers including predicted therapeutic windows, patient stratification criteria, and biomarker profiles.

View our current pipeline →

Platform Performance

93.3%
GPQA Diamond Accuracy
Highest score on PhD-level science benchmark. Learn more →
100x
Faster Target Discovery
Weeks instead of years to identify validated drug targets
4
Active Pipeline Programs
Oncology, infectious disease, hematology, cardiovascular
24/7
Autonomous Operation
AI scientists work continuously without human intervention

Frequently Asked Questions

How does Omic's AI drug discovery work?

Omic's platform integrates multi-omics data to build digital patient models. Autonomous AI scientists analyze these models to discover drug targets, design novel molecules, and simulate clinical outcomes—all computationally before wet lab work begins.

How accurate is Omic's AI?

Omic achieves 93.3% accuracy on the GPQA Diamond benchmark—the highest score of any AI system on PhD-level science questions. Our digital patient models demonstrate strong predictive accuracy for drug response across multiple therapeutic areas.

What makes Omic different from other AI drug discovery companies?

Omic uniquely combines: (1) Autonomous AI scientists that independently form and test hypotheses; (2) Mechanistic digital patient models built from multi-omics data; (3) End-to-end discovery from target identification through virtual clinical trials.

How long does AI drug discovery take with Omic?

Omic identifies validated drug targets in weeks rather than years. The complete discovery cycle from target identification to clinical candidate nomination typically takes 3-6 months, compared to 3-5 years for traditional approaches.

Ready to accelerate your drug discovery?

Partner with Omic to discover drugs faster, with higher success rates.

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