MYR-001: Cancer & infectious disease
A small-molecule program targeting protein N-myristoylation — a dependency shared across certain cancers and infectious agents.
Program Overview
Scientific Rationale
A shared cellular dependency
N-myristoylation is a lipid modification that many proteins require to localize correctly and function. A range of tumors and infectious pathogens rely on this pathway more heavily than healthy human cells, which opens a potential therapeutic window.
One mechanism, two indications
Because the same enzymatic dependency appears in both oncology and infectious-disease settings, a single small-molecule series has the potential to address multiple indications from a common chemical starting point.
Our Approach
AI-guided discovery
Omic screened large chemical spaces against the pathway and used disease-specific digital patients to prioritize candidates predicted to be selective for diseased over healthy cells.
Where it stands
The program is in lead optimization, refining potency, selectivity, and drug-like properties. The specific molecular target remains undisclosed.
Program details, including specific molecular targets, are disclosed selectively under confidentiality as part of partnership and licensing discussions.
Interested in Licensing MYR-001?
Contact us to discuss licensing opportunities and partnership terms